Synthetic genetics: beyond DNA and RNA

Digitale Veranstaltung
Foto: LMB picture official

Synthetic biology seeks to probe fundamental aspects of biological form and function by construction (i.e. resynthesis) rather than deconstruction (analysis). Synthesis thus complements reductionist and analytic studies of life, and allows novel approaches towards fundamental biological questions.
We have been exploiting the synthesis paradigm to explore the chemical etiology of the genetic apparatus shared by all life on earth. I will present recent progress in the development and application of strategies to enable the replication and evolution of synthetic genetic polymers not found in nature, which we term XNAs. Furthermore, I will present our progress in the engineering and evolution of RNA polymerase ribozymes towards self-replication.
 
Philipp Holliger is a Program Leader at the UKRI MRC Laboratory of Molecular Biology (MRC LMB) in Cambridge. He graduated from the Swiss Federal Institute of Technology (ETH) Zürich with distinction. He then moved to Cambridge for a Ph. D. and a postdoctoral fellowship with Greg Winter (Nobel prize Chemistry 2018). In 2000, he joined the faculty at MRC LMB, where he was tenured in 2005. His research spans the fields of chemical biology, synthetic biology and in vitro evolution and has been published in major journals (e. g. Nature, Science, Cell etc.) and has featured in Scientific American’s 10 World Changing Ideas. He was elected member of EMBO in 2015.

Moderation: Professorin Dr. Sabine Müller

-------

Organizational information on the digital lecture
The Alfried Krupp Wissenschaftskolleg is offering this event live as a zoom meeting, in which viewers can also take part in the subsequent discussion with video contributions.

  • We would be delighted if you gave your real name when dialing into Zoom. Of course, you can also take part in the event under a pseudonym.
  • A list of all participants is available to all those involved during the entire event.
  • During the lecture, the microphones of the audience are all automatically muted so as not to generate any disturbing background noise. You can turn on the audience's camera during the lecture.
  • In the discussion that follows, requests to speak or questions can be displayed using the "Raise hand" function. You can find these - depending on the device - under the button "Participant", "More" or "Reactions" in Zoom. You can also lower your hand again if you want to withdraw the question.
  • The moderator keeps a speech list and gives the floor in the order of the messages. If the moderator asks you to bring your question or request to speak, the user interface will ask you to turn on your microphone. If you have not already done so, you are welcome to turn on your camera. This is particularly desirable when presenting longer requests to speak so that the presenter can also see who is asking the question or who is making the comment.
  • Of course, you also have the option of asking your questions in writing in the chat.

-------

Access to the Digital Lecture

Meeting-ID: 821 1790 3697
Kenncode: WIKO2021

-------

Ähnliche Veranstaltungen


Zurück zu allen Veranstaltungen