Molecules at the origin of life: functional diversity of a small catalytic RNA

Abendvortrag mit Anmeldung,Digitale Veranstaltung
Fotografie: Vincent Leifer

Functional RNAs that contribute to higher genetic complexity and expanded functional space are of great importance for scenarios of early life, i.e. in the RNA world.  The lecture will introduce ribozyme variants that perform RNA processing reactions in different scenarios, including RNA recombination, regular and back-splicing. Recent studies on the activity of encapsulated ribozymes clearly show that encapsulation in vesicles supports intermolecular association and structure formation and thus overall activity of catalytic RNAs compared to their activity in free solution. This confirms the importance of compartmentalization for further evolution of functionality.

Sabine Müller holds the Chair of Biochemistry/Bioorganic Chemistry at the University Greifswald. After her academic graduation from Humboldt University Berlin, she worked for 18 months as a postdoc at the MRC in Cambridge, UK, and then took up a group leader position again at Humboldt University. After her habilitation in 2003, she moved to the Ruhr University Bochum, where she held a professorship in bioorganic chemistry, before accepting her current appointment at the University of Greifswald in 2006. Sabine Müller‘s research focuses on the chemistry and biochemistry of nucleic acids.

Moderation: Professorin Dr. Ulla Bonas

Registration for face-to-face participation


Organizational information on the digital lecture
The Alfried Krupp Wissenschaftskolleg is offering this event live as a zoom meeting, in which viewers can also take part in the subsequent discussion with video contributions.

  • We would be delighted if you gave your real name when dialing into Zoom. Of course, you can also take part in the event under a pseudonym.
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  • During the lecture, the microphones of the audience are all automatically muted so as not to generate any disturbing background noise. You can turn on the audience's camera during the lecture.
  • In the discussion that follows, requests to speak or questions can be displayed using the "Raise hand" function. You can find these - depending on the device - under the button "Participant", "More" or "Reactions" in Zoom. You can also lower your hand again if you want to withdraw the question.
  • The moderator keeps a speech list and gives the floor in the order of the messages. If the moderator asks you to bring your question or request to speak, the user interface will ask you to turn on your microphone. If you have not already done so, you are welcome to turn on your camera. This is particularly desirable when presenting longer requests to speak so that the presenter can also see who is asking the question or who is making the comment.
  • Of course, you also have the option of asking your questions in writing in the chat.


Access to the Digital Lecture

Meeting-ID: 929 6384 7082
Kenncode: Wiko2021


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