Multicellularity as an emergent property of life: Spatial organisation of molecular signaling and gene expression in bacterial biofilms

Digital Lecture
Foto: Emmanuel Aronis

An overarching theme of cellular regulation in bacteria arises from the trade-off between growth and stress resilience. In addition, the formation of biofilms contributes to stress survival, since these dense multicellular aggregates, in which cells are embedded in an extracellular matrix of self-produced polymers, represent a self-constructed protective and homeostatic ‚niche‘. As will be shown for the model bacterium E. coli, biofilm control is achieved by a highly integrated regulatory network that promotes either growth or stress resistance and organizes 3D multicellularity in a world of limited resources.

Regine Hengge studied Biology and obtained her doctorate at Universität Konstanz. After a post-doctoral phase at Princeton University (USA), she completed her Habilitation in Microbiology and Molecular Genetics at Universität Konstanz. She has been a Full Professor of Microbiology at Freie Universität Berlin (1998-2013) and Humboldt-Universität zu Berlin (since 2013). Regine Hengge received the Gottfried Wilhelm Leibniz Prize and an ERC Advanced Investigator Grant. She is an elected member of Leopoldina, BBAW, EMBO and the American Academy of Microbiology.

Moderation: Professorin Dr. Katharina Riedel

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Organizational information on the digital lecture
The Alfried Krupp Wissenschaftskolleg is offering this event live as a zoom meeting, in which viewers can also take part in the subsequent discussion with video contributions.

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